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     ,        .     .  COVID-19      렖  ,     .          ,             . , COVID-19     ,    ,       19181920. ( ,    100 [1 - https://www.visualcapitalist.com/history-of-pandemics-deadliest/ (https://www.visualcapitalist.com/history-of-pandemics-deadliest/).]).     :    10%  .      ,         .

 ,              .          ,        . ,  ,  ,         ,   ,    COVID-19.      ,   ,             .

 .     ,       ,           . ,   ,  ,        .           ,        .           ,            ,  . ,  ,  ,               .

,       ,         ,              510.          ,      .  ,     ,       .    ,          .  ,          ,    ,     (    ,   COVID-19,  ,  20   SARS,    , 40     ).

         ,      .            ,  , ,  , , ,   ,     ,    . ,  ,      ,   !

         蠖   .        ,     蠖        .      ,     ,   .      , , , , , , , ,    .         ?  2018.      ,      .               ?

    - .           .      ,       .   ,      2050.    -    [2 - https://www.fightaging.org/archives/2020/08/the-reasons-to-study-aging/ (https://www.fightaging.org/archives/2020/08/the-reasons-to-study-aging/).].       ,      ,     -  .          .

    65 ,      5,     .  ,      ,    , ,    .  ,       The Lancet,  2100.     ,   732 [3 - https://www.thelancet.com/infographics/population-forecast (https://www.thelancet.com/infographics/population-forecast).].   ,        ,   ,   ,    .     ,   .         .

    ,         Science, ,  COVID-19       11     ,   ,                 26 [4 - https://www.statista.com/chart/22378/estimated-cost-of-containing-future-pandemic/ (https://www.statista.com/chart/22378/estimated-cost-of-containing-future-pandemic/).].      10%  ,  蠖  -  ࠖ   .   ,         ,   .   ,      ;      [5 - http://www.sjayolshansky.com/sjo/Longevity_Dividend_Initative.html (http://www.sjayolshansky.com/sjo/Longevity_Dividend_Initative.html).].           ,        ,    ,     .

, COVID-19  ,              .  ,           ⻠ .          ?

   .      .     ?



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,   ,    ,     -        .    , ,             ,     ,       30      .         ,      :           ,   . ,        .           蠖     .

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 蠖    ,      ,  ,       .        ,       .      ,          , ,      !

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      (La Muerte de la Muerte, Editorial Planeta, 2018)       ,       . ,    (a Morte da Morte, LVM Editora, 2019),   젖   ,   .              ,   , , , , , ,   .      ,  ,  , ,     .

 ,              .   ,        ,        ,    .  !



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   [6 -   .  . .:   , 2011.]     SENS Research Foundation







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  ,    .

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  .    .    ,     .

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       .

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       .         ,  ,  .    ,     Homo sapiens sapiens[7 -  . Homo sapiens sapiens ( )   ,   ;     .],                    ,      .  ,       ,       .           .


  

   :         (Immortality: The Quest to Live Forever and How It Drives Civilization)  ,     , [8 - https://www.amazon.com/Immortality-Quest-Forever-Drives-Civilization/dp/1510716157 (https://www.amazon.com/Immortality-Quest-Forever-Drives-Civilization/dp/1510716157).]:     ,      .  ,         :   ,  ,       .     ,       .

      .         ,    .   仠  ,   ,   ,       ,       ,      .      ,     ,      2400.  ..

      (    ,      ,   1550  50.  ..). ꠖ     젖     ,       (    )           .          ,      ,         [9 - https://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/">https://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/ (https://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/%22%3Ehttps://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/).].

            ,   2500.  ..   ,     ,      ,  ,     .         ,     ,     . ,     ,           ,   .         ,        [10 - https://www.amazon.com/Epic-Gilgamesh/dp/014044100X"> (https://www.amazon.com/Epic-Gilgamesh/dp/014044100X%22%3E).].

  ,   ,     .       221.  ..        ࠖ       .  ,      ,    ,         ,  ,   ( ,    , ,        )[11 - https://www.amazon.com/First-Emperor-China-Jonathan-Clements-ebook/dp/B00XJIQ7K2/ (https://www.amazon.com/First-Emperor-China-Jonathan-Clements-ebook/dp/B00XJIQ7K2/).].

    ,    ,   212.  ..    [12 - ?? ()    ,  , ; .: .].   ,       (, )    .   :         . ,    ,  , ,   ,    .             8000   520 .      1974.    ,        .

   , ,   ,    .               ,  .        (,     )     .          ,        , ,   .

           .        ,     . ,            .  , ,      ,   325.  ..     .     ,           .  ,   ,      ,      .

 蠖      ,        .  ,   ,          .         ,   IV.  ..        ,      ,   , .        ,      .        ,    .          ,  ,   ,   .

             蠖     -   (,    ).  ,       [13 - ࠖ   .],   -.            .              -,   ,       1513.,     .     ,        [14 - https://www.amazon.com/EUROPEAN-DISCOVERY-AMERICA-D-1492-1616/dp/B000J57YR8 (https://www.amazon.com/EUROPEAN-DISCOVERY-AMERICA-D-1492-1616/dp/B000J57YR8).].

     ,     堖 , ,    ( ),        .  ,    ,     蠖 ,   ,     .   ,    ,    ,            .  ,        , ,       .

       ,       ,     : Sapiens.   [15 -  . Sapiens:   . .: , 2017.]  Homo Deus.   [16 -  . Homo Deus:   . .: , 2018.].         Homo sapiens    XXI.     頖   .

     ,      .     ,    ,            .   ,     ,    XXI:         ().          [17 - http://www.openthemagazine.com/article/essay/the-last-days-of-death (http://www.openthemagazine.com/article/essay/the-last-days-of-death).]:



  ,  XXI      .              .             .  ,        ,   ,   .     ,   ,   ,    .    ,         (,    ,      ),  ,         .      , , ࠖ   ,       .

 ,       .     ,  ,  ,    ,       .      .  ,    ,          ,        .        ,      ,   .     ,   ,         .    ,     ,   ,       ,  .

           .                 .      ,      .



   

    ,     ,   .     1953.     .   ,       ,    .       1967.,    1980.,       ,   (,      CRISPR/Cas9),    3D- .

    ,    ,     (Big data),       ,                ,   ,  .   ,      .

      1990.,   1997.        .      ,     99%  .  ,     ,   2003.   .      ,  1997.      .  1998.   2% ,  1999. 4%,  2000. 8%,  2001. 16%,  2002. 32%,  2003. 64%,        [18 - https://www.youtube.com/watch?v=h6tYxQnxRj8 (https://www.youtube.com/watch?v=h6tYxQnxRj8).].

   ,          .     ,          ,    .   ,              ,   , ,   .

       ,               .      -[19 - -ࠖ         .]    ,        . ,        ,       ,      ,     40%  [20 - http://www.encuentroseleusinos.com/work/maria-blasco-directora-del-cnio-envejecer-es-nada-natural/ (http://www.encuentroseleusinos.com/work/maria-blasco-directora-del-cnio-envejecer-es-nada-natural/).].   ,       ,           40%[21 - https://elpais.com/elpais/2016/12/15/ciencia/1481817633_464624.html (https://elpais.com/elpais/2016/12/15/ciencia/1481817633_464624.html).].  ,   ,        .

-    : , ,   ,   ࠖ    MPrize ,    [22 - https://www.mfoundation.org/ (https://www.mfoundation.org/).].    ,       180 [23 - https://web.archive.org/web/20190324131618/ (https://web.archive.org/web/20190324131618/), http://www.sens.org/outreach/conferences/methuselah-mouse-prize (http://www.sens.org/outreach/conferences/methuselah-mouse-prize).],      ,  ,   .

     :     (   , -  ),       (,      90% ).      ,       ,  ,   ,  .   ,     .          ,  ,     . ,       ,          堖  .    ,       (-       ),      .

     ,      .         . ,         [24 - https://www.faculty.uci.edu/profile.cfm?faculty_id=5261 (https://www.faculty.uci.edu/profile.cfm?faculty_id=5261).]        ,             C. elegans    10[25 - https://uams-triprofiles.uams.edu/profiles/display/127822 (https://uams-triprofiles.uams.edu/profiles/display/127822).]. ( :        ,       .)

                  .  ,    ,          .     ,   .   ,    (   PayPal),   (Amazon),   (Facebook),   (Oracle),      (Alphabet/Google)    ,    .    [26 - http://time.com/574/google-vs-death/ (http://time.com/574/google-vs-death/).] Google  2013.   Calico (California Life Company), Microsoft  2016. ,    10  [27 - http://www.telegraph.co.uk/science/2016/09/20/microsoft-will-solve-cancer-within-10-years-by-reprogramming-dis/ (http://www.telegraph.co.uk/science/2016/09/20/microsoft-will-solve-cancer-within-10-years-by-reprogramming-dis/).].        ,                 [28 - http://www.businessinsider.com/mark-zuckerberg-cure-all-disease-explained-2016-9 (http://www.businessinsider.com/mark-zuckerberg-cure-all-disease-explained-2016-9).].       ,    ,      .

       .       ,      ׸,     ,         ,     ,   ,     (            ). ׸,     ,         ,  [29 - https://endpoints.elysiumhealth.com/george-church-profile-4f3a8920cf7g-4f3a8920cf7f (https://endpoints.elysiumhealth.com/george-church-profile-4f3a8920cf7g-4f3a8920cf7f) ( ).]:



,           .   ,          ,     .       ,     .


  ,     ,        .   ,   ,   .    1964.                 [30 - http://www.amazon.com/Pleasure-Finding-Things-Out-Richard/dp/0465023959 (http://www.amazon.com/Pleasure-Finding-Things-Out-Richard/dp/0465023959).][31 -  .  . .: , 2013.]   ,        :



    頖        .      ,  ,    ,         ;      .       , ,      .  ,            ,   ,     ,       ,    .


     ,       ,       .     Aging[32 -  . aging .],    2009.       : ,    (Aging: Past, Present and Future)    :      ,       ,  [33 - https://dash.harvard.edu/bitstream/handle/1/4931360/2815757.pdf?sequence=1&isAllowed=y (https://dash.harvard.edu/bitstream/handle/1/4931360/2815757.pdf?sequence=1&isAllowed=y).]:



  [34 -       :   .],   1950- .,    ,    .     . ,      ,   .  ,           . ,      , ,            .




  ,           [35 -  .-. ???? , .],      .  1889.  : ,      ,           .




           1980- .       , [36 - http://dx.doi.org/10.1016/0047-6374(83)90082-9 (http://dx.doi.org/10.1016/0047-6374(83)90082-9).]       C. elegans,     ,   ,    ( age-1)     .  1993.   ,    , ,     daf-2     C. elegans           .      ,  daf-2      𔠖   ,     -       .    ,        ,  ,         ,        .


     ,    XIX.  ,    XX.,       .    ,     ,      - C. elegans   1980- .      ,               .

         ,      .   ,     .    ,    ,           ,      .         ,     ,   .       ,                . , ,     ,    ,   ,        .          ,    ,  ,    .,       .

,          ,     ,            . ,     ,     ,     (   , , , FOXO, -1, mTOR, , PI3K, , TOR   ,   ).    ,         ,       .     :






      ,  ,  ,        ,      .   ,      ,  .   [37 - ,  SIR2, ( . Silent information regulation   ) ,       .],         .      TOR.     TOR        .   ,                  ,    ,   ,  .  (    ),    TOR,       .

 ,            ( ,    , )  ,        .

        Aging   Impact.     ,        ,       ,      ,     ,   ,        .       (-,  - , -  - ,    ,   FOXO, , PI3K,   mTOR)    .       ,    , ,   - , ,  ,    ,   ,  ,      ,  ,  ,  II ,    .      ,        . ,          ,  ,    蠖   .


    2009.                 頖  CRISPR.     1980- .,        XXI.       2003.,        2006.    ,    2006.,        2010- .      Aging     ,         .    ,     .    ,           ,      .  ,    -     ,        .




  .


   .

   ,     (https://www.litres.ru/pages/biblio_book/?art=65457147)  .

      Visa, MasterCard, Maestro,    ,   ,     ,  PayPal, WebMoney, ., QIWI ,       .



notes








1


https://www.visualcapitalist.com/history-of-pandemics-deadliest/ (https://www.visualcapitalist.com/history-of-pandemics-deadliest/).




2


https://www.fightaging.org/archives/2020/08/the-reasons-to-study-aging/ (https://www.fightaging.org/archives/2020/08/the-reasons-to-study-aging/).




3


https://www.thelancet.com/infographics/population-forecast (https://www.thelancet.com/infographics/population-forecast).




4


https://www.statista.com/chart/22378/estimated-cost-of-containing-future-pandemic/ (https://www.statista.com/chart/22378/estimated-cost-of-containing-future-pandemic/).




5


http://www.sjayolshansky.com/sjo/Longevity_Dividend_Initative.html (http://www.sjayolshansky.com/sjo/Longevity_Dividend_Initative.html).




6


  .  . .:   , 2011.




7


 . Homo sapiens sapiens ( )   ,   ;     .




8


https://www.amazon.com/Immortality-Quest-Forever-Drives-Civilization/dp/1510716157 (https://www.amazon.com/Immortality-Quest-Forever-Drives-Civilization/dp/1510716157).




9


https://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/">https://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/ (https://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/%22%3Ehttps://www.amazon.com/Egyptian-Book-Dead-Integrated-Full-Color/dp/1452144389/).




10


https://www.amazon.com/Epic-Gilgamesh/dp/014044100X"> (https://www.amazon.com/Epic-Gilgamesh/dp/014044100X%22%3E).




11


https://www.amazon.com/First-Emperor-China-Jonathan-Clements-ebook/dp/B00XJIQ7K2/ (https://www.amazon.com/First-Emperor-China-Jonathan-Clements-ebook/dp/B00XJIQ7K2/).




12


?? ()    ,  , ; .: .




13


ࠖ   .




14


https://www.amazon.com/EUROPEAN-DISCOVERY-AMERICA-D-1492-1616/dp/B000J57YR8 (https://www.amazon.com/EUROPEAN-DISCOVERY-AMERICA-D-1492-1616/dp/B000J57YR8).




15


 . Sapiens:   . .: , 2017.




16


 . Homo Deus:   . .: , 2018.




17


http://www.openthemagazine.com/article/essay/the-last-days-of-death (http://www.openthemagazine.com/article/essay/the-last-days-of-death).




18


https://www.youtube.com/watch?v=h6tYxQnxRj8 (https://www.youtube.com/watch?v=h6tYxQnxRj8).




19


-ࠖ         .




20


http://www.encuentroseleusinos.com/work/maria-blasco-directora-del-cnio-envejecer-es-nada-natural/ (http://www.encuentroseleusinos.com/work/maria-blasco-directora-del-cnio-envejecer-es-nada-natural/).




21


https://elpais.com/elpais/2016/12/15/ciencia/1481817633_464624.html (https://elpais.com/elpais/2016/12/15/ciencia/1481817633_464624.html).




22


https://www.mfoundation.org/ (https://www.mfoundation.org/).




23


https://web.archive.org/web/20190324131618/ (https://web.archive.org/web/20190324131618/), http://www.sens.org/outreach/conferences/methuselah-mouse-prize (http://www.sens.org/outreach/conferences/methuselah-mouse-prize).




24


https://www.faculty.uci.edu/profile.cfm?faculty_id=5261 (https://www.faculty.uci.edu/profile.cfm?faculty_id=5261).




25


https://uams-triprofiles.uams.edu/profiles/display/127822 (https://uams-triprofiles.uams.edu/profiles/display/127822).




26


http://time.com/574/google-vs-death/ (http://time.com/574/google-vs-death/).




27


http://www.telegraph.co.uk/science/2016/09/20/microsoft-will-solve-cancer-within-10-years-by-reprogramming-dis/ (http://www.telegraph.co.uk/science/2016/09/20/microsoft-will-solve-cancer-within-10-years-by-reprogramming-dis/).




28


http://www.businessinsider.com/mark-zuckerberg-cure-all-disease-explained-2016-9 (http://www.businessinsider.com/mark-zuckerberg-cure-all-disease-explained-2016-9).




29


https://endpoints.elysiumhealth.com/george-church-profile-4f3a8920cf7g-4f3a8920cf7f (https://endpoints.elysiumhealth.com/george-church-profile-4f3a8920cf7g-4f3a8920cf7f) ( ).




30


http://www.amazon.com/Pleasure-Finding-Things-Out-Richard/dp/0465023959 (http://www.amazon.com/Pleasure-Finding-Things-Out-Richard/dp/0465023959).




31


 .  . .: , 2013.




32


 . aging .




33


https://dash.harvard.edu/bitstream/handle/1/4931360/2815757.pdf?sequence=1&isAllowed=y (https://dash.harvard.edu/bitstream/handle/1/4931360/2815757.pdf?sequence=1&isAllowed=y).




34


      :   .




35


 .-. ???? , .




36


http://dx.doi.org/10.1016/0047-6374(83)90082-9 (http://dx.doi.org/10.1016/0047-6374(83)90082-9).




37


,  SIR2, ( . Silent information regulation   ) ,       .


